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Research report

Payer Mix Analysis: Autoimmune Encephalitis (AIE) and Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)

24 January 2023

UCB recently engaged Milliman to estimate the distribution of patients with autoimmune encephalitis (AIE) or myelin oligodendrocyte glycoprotein antibody-associated disease (MOG-AD). AIE is a group of autoimmune disorders that affect the brain and cause inflammation of the brain. MOG-AD is a disorder caused by inflammatory attacks of the central nervous system. Milliman conducted a claims-based analysis for AIE, as well as a literature-based analysis for AIE and MOG-AD. The following payer channels are included in the analysis: 

  • Medicare Fee-for-Service (FFS)
  • Medicare Advantage
  • Commercial
  • Medicaid (FFS and managed care)

This report was commissioned by UCB, Inc.


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